AI-Powered Longevity Research Platform

AI that designs drugs
to reverse aging

Chronos Bio is building the intelligence platform for longevity research. Multi-omics biological age. Senolytic compound screening. Cellular reprogramming design. Compressing decades of aging research into years.

100,000 people die from aging every day. We are building the AI to change that.

100K
Daily deaths from age-related causes
$120B
Anti-aging market by 2030
50x
AI improvement in cell reprogramming
100x
Cost reduction in senolytic screening
The Problem

Aging is the largest unsolved problem
in human history.

Aging kills more people than every other cause combined. Cancer, heart disease, neurodegeneration, diabetes, organ failure -- they are all symptoms of the same underlying process: cellular aging. Yet we spend trillions treating each symptom individually while the root cause goes unaddressed.

The cost is staggering. Age-related diseases consume over $8.3 trillion annually in the US alone -- 80% of all healthcare spending. By 2050, 2.1 billion people will be over 60 (WHO), placing unsustainable strain on every healthcare system on Earth.

The longevity research field is fragmented across thousands of labs, each studying one piece of the aging puzzle in isolation. No platform integrates the 12 hallmarks of aging into a unified model. No tool can screen millions of potential anti-aging compounds computationally. The search space is in the billions -- and researchers test hundreds per year, manually.

100,000/day
People who die from age-related causes
$8.3T/year
US healthcare cost of age-related diseases
~30
Total validated senolytic compounds discovered
Our Solution

The intelligence platform for longevity research.
Measure. Screen. Design.

Chronos Bio builds the AI platform that every longevity researcher and pharma R&D team needs. Multi-omics biological age intelligence, senolytic compound screening, and cellular reprogramming optimization -- all in one platform.

MODULE 01

ChronosClock

Multi-Omics Biological Age

Compute biological age from blood biomarkers using multiple published aging clocks. Get a multi-dimensional aging profile: inflammation, metabolic health, immune aging, organ function. Track how interventions change your biological age over time.

MODULE 02

SenolyticsEngine

AI Compound Screening

Screen any compound for senolytic activity using AI trained on published screening data. Predict mechanism of action, selectivity across senescent cell types, and toxicity. Compare against all known senolytics. Discover novel candidates from millions of molecules.

MODULE 03

ReprogramOS

Cellular Rejuvenation Design

AI-designed reprogramming factor optimization. Following the GPT-4b micro paradigm, use protein language models to design safer, more effective transcription factors for cellular rejuvenation. Optimize multi-factor cocktails for tissue-specific reprogramming.

Multi-clock biological age
800K+ compounds screened
Public aging databases
100x faster drug screening
Market Opportunity

The $120B longevity market needs an AI brain

$120B
TAM by 2030
Global anti-aging market (Grand View Research)
$18B
SAM by 2030
AI drug discovery for aging
25-30%
CAGR
Longevity biotech sector growth

Retro Biosciences targeting $5B valuation

Sam Altman-backed aging startup. OpenAI/Retro collaboration achieved 50x reprogramming improvement. Dec 2025.

Altos Labs raised $3B for cellular reprogramming

Largest private longevity funding ever. Recruited Steve Horvath and Morgan Levine from top universities.

NewLimit raised $130M for epigenetic reprogramming

Largest longevity-specific funding round of 2025. Coinbase CEO Brian Armstrong co-founded.

GLP-1 drugs proved aging-adjacent therapeutics work

Ozempic/Wegovy generate $20B+/year. Investors now believe longevity drugs can be blockbusters.

Why Now

The AI inflection point for longevity

Three converging breakthroughs in 2024-2026 make Chronos Bio possible for the first time. AI can now design better reprogramming factors than humans, predict biological age from multi-omics data, and screen hundreds of thousands of senolytic candidates computationally.

Design

AI Protein Engineering

OpenAI + Retro Biosciences, 2025

GPT-4b micro redesigned Yamanaka reprogramming factors with 50x improved efficacy and fewer DNA breaks. AI can now design biological interventions that surpass 20 years of human research. The paradigm shift: AI designs the drugs, not just screens them.

Measure

Multi-Omics Aging Clocks

OMICmAge, Nature Aging 2026

Third-generation clocks integrate proteomics, metabolomics, clinical data, and DNA methylation. OMICmAge predicts mortality better than any single-omic clock. ClockBase Agent uses LLMs to generate and test aging hypotheses across 2M+ samples. The measurement problem is being solved.

Screen

ML Senolytic Screening

Nature Communications, 2023

Machine learning screened 4,340 compounds and discovered 3 novel senolytics -- a 100x cost reduction over wet-lab approaches. Graph neural networks have now predicted activity across 800,000+ molecules. More candidates found in 2 years than the previous decade of experiments.

Technology Roadmap

Now
BioAge Explorer + Senolytic Screener
Multi-clock biological age from blood panels. AI senolytic activity prediction for any compound.
6 mo
Multi-omics integration
Integrate proteomics, metabolomics, and methylation data into unified aging intelligence.
12 mo
Generative senolytic design
AI generates novel senolytic compounds optimized for efficacy, selectivity, and safety.
24 mo
ReprogramOS launch
AI-designed reprogramming factor variants for tissue-specific cellular rejuvenation.
5 yr
Integrated aging reversal platform
Measure, screen, design, and validate anti-aging interventions. Powering every longevity lab on Earth.
Team

Built by an AI-native founder

AP

Avi Pilcer

Founder and CEO

15+ years in AI/ML. Former Head of AI Innovation at Motorola Solutions. Computational biology research at Bar-Ilan University (BINA) -- direct experience modeling complex biological systems and molecular dynamics. Founder of Ultra Deep Tech (AI safety lab). Deep reinforcement learning expertise from algorithmic trading at Geyser Light Capital. M.Sc. Industrial Engineering, B.Sc. Mathematics and Physics.

LinkedIn Profile

Why AI-native matters for longevity

Longevity research has been dominated by wet-lab biologists who test one compound at a time. AI changes the game by screening millions of candidates, integrating multi-omics data, and designing novel interventions computationally. An AI-native founder with computational biology experience bridges the gap between ML capability and biological understanding -- exactly what the field needs to accelerate from academic curiosity to clinical impact.

Seeking Domain Advisors

Aging biology, senolytic drug discovery, epigenetics, cellular reprogramming, clinical gerontology

Building a Founding Team

ML engineers, computational biologists, aging researchers. Get in touch

Roadmap

The path to reversing aging

1
Months 1-3

Platform MVP launch + first users

BioAge Explorer and Senolytic Screener live. First 500 researchers and biohackers on the platform.

2
Months 4-6

Pre-seed fundraise + team building

Raise $1.5M. Hire founding ML engineer and computational biologist.

3
Months 7-12

Enterprise API + multi-omics expansion

Enterprise screening API for pharma R&D. Multi-omics aging clock integration. Academic lab partnerships.

4
Year 2

Seed raise + generative chemistry

Raise $4M. AI-designed novel senolytic compounds. First wet-lab validation partnerships.

5
Year 3+

Series A + ReprogramOS

AI-designed reprogramming factors. Validated drug candidates. The standard platform for longevity AI.

Early Access

Join the fight against aging

Chronos Bio is in development. Join the waitlist to get early access to BioAge Explorer and Senolytic Screener. Longevity researchers and biotech professionals get priority.

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